Isatis root polysaccharide promotes maturation and secretory function of monocyte-derived dendritic cells
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چکیده
منابع مشابه
Maturation State and Function of Monocyte Derived Dendritic Cells in Liver Transplant Recipients
Background: Dendritic cells (DCs) are potent antigen presenting cells for triggering of the immune reaction post transplantation. These cells are centrally involved in the initiation of T cell-dependent immune responses. Objective: To compare the level of DC maturation and function in liver transplant recipients with healthy controls. Methods: In this study, twelve peripheral blood samples we...
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Background & Objectives: Interaction of cytomegalovirus glycoprotein B with toll-like receptors of dendritic cells leads to early signaling and innate immune responses. The aim of this study is to evaluate the effects of cytomegalovirus glycoprotein B on the maturation and function of monocyte-derived dendritic cells in treated groups in comparison with control groups. Materials & Methods: Bloo...
متن کاملmaturation state and function of monocyte derived dendritic cells in liver transplant recipients
background: dendritic cells (dcs) are potent antigen presenting cells for triggering of the immune reaction post transplantation. these cells are centrally involved in the initiation of t cell-dependent immune responses. objective: to compare the level of dc maturation and function in liver transplant recipients with healthy controls. methods: in this study, twelve peripheral blood samples were...
متن کاملDIFFERENTIATION OF MONOCYTE DERIVED DENDRITIC CELLS IN SERUM FREE CONDITIONS
Human peripheral blood monocytes (HPBM) were cultured in the absence of human serum and were converted into a state exhibiting a high accessory function expressed by their ability of supporting lymphocyte proliferation. After a prolonged culture in serum free media the monocyte derived cells were highly viable, increased in size and developed veils and dendritiform elongatio'l1s. Paralleli...
متن کاملGeneration of Mature Monocyte-Derived Dendritic Cells in the Presence of Heparin and Monocyte Conditioned Medium: Phenotypic and Functional Comparison
Background: Dendritic cells (DC) induce tumor or pathogen-specific T cell responses in humans. Several laboratories have developed culture systems, including maturation factors for human DC from peripheral blood monocytes. We comprehensively compared standard maturation stimulus, an autologous monocyte-conditioned medium (MCM), with heparin for their ability to promote uniformly mature DC that ...
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ژورنال
عنوان ژورنال: BMC Complementary Medicine and Therapies
سال: 2020
ISSN: 2662-7671
DOI: 10.1186/s12906-020-03103-2